The purpose of this study is to investigate the epidemiology of resistant hypertension, evaluate the efficacy and feasibility of a standardized drug treatment regimen (including the randomization of two doses of the diuretic used - chlorthalidone), study two interventions in the group of patients that is non-compliant, and study environmental and genetic variables of individuals with resistant hypertension in a family design.
Study Type
OBSERVATIONAL
Enrollment
74
chlorthalidone 25mg/d vs. chlorthalidone 50mg/d
motivational interview(s) vs. repeated calls vs. no particular intervention
olmesartan, amlodipine, chlorthalidone, +- spironolactone
Geneva University Hospitals
Geneva, Switzerland
Lausanne University Hospital, CHUV
Lausanne, Switzerland
Kantonsspital Luzern
Lucerne, Switzerland
blood pressure control
Time frame: at 12 weeks after initiation of standard treatment
cardiovascular morbidity and mortality
additional secondary: BP control at yearly follow-up
Time frame: 5 years
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