Sudden cardiac arrest (SCA) remains one of the major leading causes of death. Cognitive deficits are common in survivors of SCA. Postresuscitative mild induced hypothermia (MIH) lowers mortality and reduces neurologic damage after cardiac arrest. The investigators evaluated the long term neurological outcome after mild hypothermia after restoration of spontaneous circulation.
Consecutive patients with restoration of spontaneous circulation (ROSC) after resuscitation due to out-of-hospital SCA, admitted to our intensive care unit, underwent MIH. Hypothermia was induced by infusion of cold saline and whole-body-cooling methods (electronic randomization: invasive Coolgard or non-invasive ArcticSun). The core body temperature was operated at 32 to 34 °C over a period of 24 hours followed by active rewarming. Neurological status was evaluated at hospital discharge and 6 months after discharge using the Pittsburgh Cerebral Performance Category (CPC).
Study Type
OBSERVATIONAL
Enrollment
150
University of Leipzig, Heart Center, Cardiology
Leipzig, Germany
RECRUITINGNeurological outcome after 6 month after MIH, Quality of life-survey
Neurological outcome after 6 month after MIH measured by questionnaire.
Time frame: 6 Month
Managing daily activities
Managing daily activities after 6 month after tMIH measured with a questionnaire.
Time frame: 6 Month
Surviving after hospitalization
Surviving after hospitalization after MIH
Time frame: 6 Month
Neurological outcome depending of the beginning of MIH
Neurological outcome depending of the beginning of MIH
Time frame: 6 month
Neurological Outcome in consideration of the practice of the treating instances.
Neurological outcome in consideration of the practice of the treating instances after restoration of spontanous circulation measured with a questionnaire.
Time frame: 6 month
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.