Influence of different application sites on the blood levels after administration of a fertility control patch
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
43
Transdermal Patch, 0.55mg Ethinylestradiol + 2.1mg Gestodene, 4x7 days patch wearing period, patch-free interval of 7 days, application site: buttocks
Transdermal Patch, 0.55mg Ethinylestradiol + 2.1mg Gestodene, 4x7 days patch wearing period, patch-free interval of 7 days, application site: arm
Transdermal Patch, 0.55mg Ethinylestradiol + 2.1mg Gestodene, 4x7 days patch wearing period, patch-free interval of 7 days, application site: abdomen
Unnamed facility
Berlin, State of Berlin, Germany
AUC(0-168) for EE and Gestodene during week 4 of each treatment period
Time frame: Week 4 of each treatment period ( 3 periods)
Pharmacokinetic parameters of EE and GSD: Cmax, Cmin, Cav, tmax, t1/2 obtained during week 4, Ctrough obtained at the end of each week
Time frame: Week 1-5 of each treatment period
Adverse Events
Time frame: Week 1-5 of each treatment period
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