Dose Titration of Propofol for Tracheal Intubation in Children With Sevoflurane Inhalation Induction

N/ACompletedNCT01084031

Yonsei University50 enrolled

Overview

Dose titration of propofol for tracheal intubation in children with sevoflurane inhalation induction.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

DOUBLE

Enrollment

Conditions

Pediatric Urinary Disorders

Interventions

propofolDRUG

intravenous propofol with sevoflurane inhalation induction

Eligibility

Sex: ALLMin age: 6 MonthsMax age: 5 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Pediatric patients scheduled for elective day case surgery were enrolled. Exclusion Criteria: * History of obstructive sleep apnea * Evidence of cardiorespiratory disease * Those who were obese or allergic to any of the anesthetic agents in this study * Those with an anticipated difficult airway, full stomach * History of malignant hyperthermia or other myopathy were excluded.

Outcomes

Primary Outcomes

Assessment of intubation conditions

Assessment of intubation conditions (vocal cord, intubation condition, cough, movement) , peri-induction HR and BP change, post-operative agitation socre at recovery room. ED50 and ED 95 of each group by uring Dixon's up and down methods. peri -induction period -comparison of above factors among each groups (GroupA: ETSevo 3vol%, Group B: ETSevo 3.5vol%, Group: ET Sevo 4vol%)

Time frame: 30 minutes after the surgery

Data from ClinicalTrials.gov

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