Effect of Adding Sufentanil to Epidural Ropivacaine on Perioperative Metabolic and Stress Responses in Combined General/Epidural Anaesthesia for Geriatric Radical Retropubic Prostatectomy

Yonsei University60 enrolled

Overview

The purpose of this study is to compare metabolic and stress responses in combined general/epidural anesthesia in geriatric cancer patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Enrollment

Conditions

Prostatic Cancer

Interventions

epidural infusion of saline, ropivecaine, or ropivacaine and sufentanilDRUG

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * elective RRP for prostatic cancer scheduled in the morning (9-11 a.m.) * patients aged more than 65 years * ASA physical status I or II * absence of contraindications to epidural approach * absence of a history of chronic pain or opioid medication Exclusion Criteria: * contraindication to epidural catheterization

Locations (1)

Severance Hospital

Seoul, South Korea

Outcomes

Primary Outcomes

plasma glucose, insulin, cortisol, epinephrine, norepinephrine, prolactin

Time frame: from preoperative baseline to postoperative 24 hours

Data from ClinicalTrials.gov

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