This observational long-term follow-up study will evaluate demographic, clinical, histological, biochemical, and virological parameters of patients with chronic hepatitis B and low viremia who do not require antiviral therapy according to current guidelines. Liver stiffness values as detected by FibroScan and ARFI will also be collected if available. All data will be collected at yearly intervals (minimum). Patients included in the study are followed for up to 10 years. The target sample size is \<1000.
Study Type
OBSERVATIONAL
Enrollment
1,000
Charité Berlin-Campus Virchow-Klinikum
Berlin, Germany
Klinikum der J. W. Goethe-Universität
Frankfurt, Germany
Institut für Interdisziplinäre Medizin
Hamburg, Germany
Medizinische Hochschule Hannover
Hanover, Germany
Indication for Antiviral Treatment
Time frame: 10 years
Development of hepatocellular carcinoma (HCC)
Time frame: 10 years
Progression of Liver Fibrosis
Time frame: 10 years
HBV-DNA
Time frame: 10 years
Quantitative HBsAg
Time frame: 10 years
Serum ALT
Time frame: 10 years
Serum AFP
Time frame: 10 years
FibroTest/ActiTest
Time frame: 10 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Gastroenterologische Gemeinschaftspraxis Herne
Herne, Germany
Gastroenterologische Gemeinschaftspraxis Kiel
Kiel, Germany