Role of 3D Tomography in Breast Cancer

Inclusion Criteria: * All women, age 40 or older, who are scheduled for biopsy after classification as BI-RADS 4/5 and have had a screening or diagnostic full-field digital mammography (FFDM) exam are eligible to participate, except for exclusions noted below. * Able to provide informed consent. Exclusion Criteria: * Males * Women less than 40 years old * Pregnant women * Lactating women * Woman who have had bilateral mastectomies * Women with physical limitations that may prohibit resting prone on the exam table, such as, but not limited to: frozen shoulder, recent heart surgery, pace maker * Women who are unable to tolerate study constraints, frail or unable to cooperate * Women with large breasts that cannot be accommodated within the field of view of the CT system * Women who have received radiation treatments to the thorax for malignant and nonmalignant conditions, such as (but not limited to) * Treatment for enlarged thymus gland as an infant * Irradiation for benign breast conditions, including breast inflammation after giving birth * Treatment for Hodgkin's disease * Women who have participated in a prior breast clinical trial that gave additional radiation dose, such as an additional mammogram. * Women who have received large numbers of diagnostic x-ray examinations for monitoring of disease such as (but not limited to) * Tuberculosis * Severe scoliosis