Autologous Serum Skin Test and Serum IL-18 Levels in Chronic Idiopathic Urticaria and Respiratory Allergic Diseases

Eskisehir Osmangazi University

Overview

One of the proposed mechanisms in CU is autoimmunity. It was shown by a positive response to autologous serum skin test (ASST)in almost half of chronic urticaria (CU) patients. IL-18 also play a role in autoimmune disorders. The investigators aim was to investigate the relationship of ASST and IL-18 in CU and respiratory allergic diseases.

Study Type

OBSERVATIONAL

Conditions

Urticaria Respiratory Allergic Diseases

Interventions

autologous serum skin test, serum IL-18PROCEDURE

Eligibility

Sex: ALLMin age: 16 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * adult patients * chronic urticaria patients * stable asthma patients * allergic rhinitis patients with sensitized to pollens * normal controls without atopic and skin disease. Exclusion Criteria: * unwillingness to the study * other dermatological problems that could affect the skin test * use of antihistamine drugs

Locations (1)

Eskisehir Osmangazi University

Eskişehir, Turkey (Türkiye)

Data from ClinicalTrials.gov

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