Effect of Nocturnal Administration of Anti-hypertensive Medications in NoN-dippers

Yonsei University28 enrolled

Overview

The purpose of this study is to determine the effect of nocturnal administration of Anti-hypertensive medications in Non-dippers. Efficacy variables. 1. ECHO 2. 24hr. horter 3. IMT 4. BUN/crea, urine analysis (microalbulinuria 5. Cardio vascular event. "

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Hypertension

Interventions

Valsaltan, amlodipineDRUG

nti hypertensive medication time (nocturnal administration vs morning administration

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Essential hypertension (stage 1-2) 2. 24hr. holer : non-dipper 3. Age 18 \~70. Exclusion Criteria: 1. Any known malignant disease 2. Renal failure , creatinine \>2.0mg/dl 3. Liver disease

Locations (1)

Severance Hospital, Yonsei University College of Medicine

Seoul, South Korea

Outcomes

Primary Outcomes

IMT(intima media thickness) Measure data(Sono)

Time frame: baseline

IMT(intima media thickness) Measure data(Sono)

Time frame: 36 months

Data from ClinicalTrials.gov

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