Asparaginase is an important drug in the treatment of childhood leukemia. One of the rare but severe side effects to the treatment is thrombosis in or outside the central nervous system. The aim of this study is to investigate and describe the influence on the coagulation parameters during prolonged treatment with asparaginase. Hopefully this knowledge will help to foresee the risk of thrombosis and thus making it possible to prevent these.
Study Type
OBSERVATIONAL
Enrollment
65
Aalborg Hospital
Aalborg, Denmark
Department of Pediatrics, Skejby Hospital
Aarhus, Denmark
Department of Pediatrics, Rigshospitalet
Copenhagen, Denmark
University Hospital in Odense
Odense, Denmark
Description of the coagulation parameters
The study is a prospective and descriptive study. Levels of coagulation parameters will be analyzed using Two Sample T-Test and the levels of asparaginase in serum will be analyzed by Chi2 test.
Time frame: December 2016
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