Effects of Physical Exercise in Type 2 Diabetics

University Hospital, Strasbourg, France15 enrolled

Overview

The aim of this study is to evaluate the improvement in skeletal muscle energetic capacity, endothelial dysfunction and glycemic control induced by physical training in 20 sedentary patients with a type 2 diabetes.The protocol consists in a physical training program with 3 sessions of 30 minutes per week during six consecutive weeks. A skeletal muscle biopsy, a cardiac and humeral artery ultrasounds, a glycemic and tensional holters will be performed before and at the end of the physical training program.

Study Type

INTERVENTIONAL

Allocation

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Type 2 Diabetes Mellitus

Interventions

Physical exerciseBEHAVIORAL

Eligibility

Sex: ALLMin age: 40 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * sedentary adult with type 2 diabetes * BMI between 25 and 35 kg/m² * Hba1c \< 10 % Exclusion Criteria: * unstable coronary artery disease * advanced peripheral occlusive arterial disease * proteinuria \> 3 g/d and / or creatinine clearance \< 30 ml / mn * advanced diabetic neuropathy

Locations (3)

Médecine Interne et Nutrition, Hôpital Civil, Hôpitaux universitaires de Strasbourg

Strasbourg, France

Service de Physiologie et d'Explorations Fonctionnelles, Nouvel Hôpital Civil, Hôpitaux universitaires de Strasbourg

Strasbourg, France

Service de Médecine Interne et Nutrition, Hôpital de Hautepierre, Hôpitaux universitaires de Strasbourg

Strasbourg, France

Data from ClinicalTrials.gov

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