Allogeneic Hematopoietic Stem Cell Transplantation Evaluation in High Risk Myelodysplasia: an Observational Non-interventional Study

Inclusion Criteria: * 50 to 70 years * For myelodysplasia other than CMML: patients can be included if they have at least one of these criteria: 1. IPSSintermediate 1 and poor cytogenetics (complex, 3 or 7 abnormality); 2. thrombopenia \< 20x10ex9/L: 3. IPSS intermediate 2 or high * For CMML: patients can be included if they have at least one of these criteria: 1. 2 of these criteria: hyperleucocytosis \> 10x10exp9/L, splenomegaly\>18cm, hemoglobin \< 10gr/dl, platelet \< 100x10ex9/L 2. IPSS intermediate 2 or high Exclusion Criteria: * Patient not eligible for transplantation (including patients without donor)because of severe co-morbidity including: * Renal failure with creatinine clearance \< 30ml/min * Cirrhosis or hepatic failure * Respiratory disease with vital capacity \< 30% * Uncontrolled cardiac failure * Uncontrolled neurological disease * Poor performance status with karnofsky \< or = 60%