Effects of Marijuana Used on Lung Function in Persons With Chronic Obstructive Pulmonary Disease (COPD)

The University of Texas Health Science Center, Houston200 enrolled

Overview

The main hypothesis is that persons that smoke or smoked tobacco and marihuana have worsen lung function as compared with persons that only smoke or smoked tobacco.

We will follow persons with already diagnosed COPD (chronic bronchitis and/or emphysema). Obtain their smoking history: tobacco and marihuana and review their pulmonary function study results. Then we are planning to compare both groups.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Chronic Obstructive Pulmonary Disease

Eligibility

Sex: ALLMin age: 25 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * COPD patients former or current tobacco smokers * COPD patients former or current tobacco and marihuana smokers Exclusion Criteria: * History of COPD without pulmonary function testing * Refusal to provide smoking or marihuana used history

Locations (2)

Lyndon B Johnson General Hospital

Houston, Texas, United States

The University of Texas- Health Science Center at Houston

Houston, Texas, United States

Outcomes

Primary Outcomes

Obstructive limitation in pulmonary function test

Comparison on the severity of obstruction among both groups

Time frame: 1 year

Secondary Outcomes

Decreased diffusion capacity for carbon monoxide

Comparison on the severity of decreased DLco among groups.

Time frame: 1 year

Airtrapping

Comparison on the severity of air-trapping by pulmonary function testing among groups.

Time frame: 1 year

Data from ClinicalTrials.gov

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