Long Term Physical Training in Asthma

Universitätsklinikum Hamburg-Eppendorf24 enrolled

Overview

This controlled study is undertaken to investigate the effects of a long term outpatient training program on physical fitness and quality of life in elderly asthmatics.

Physical training is well known to support a healthy lifestyle. Patients with asthma are often unnecessarily restricted of physical activities or avoid exercise due to the unpleasant experience of exercise-induced dyspnea. As a consequence both children and adults with asthma are less fit than their peers. Like in healthy individuals, regular training supports health in asthmatics. In short-term training programs improvements of physical capabilities have been achieved in children and young adults with asthma. Programs of longer durations than 3 months have not been published in controlled trials. Effects of exercise training on quality of life in adult asthmatics are lacking.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Asthma

Interventions

Exercise trainingPROCEDURE

Exercise training in outpatient sport groups once weekly with a duration of 60 min each

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * physician diagnosed asthma * non-smoker * stable condition * informed consent Exclusion Criteria: * participation in pulmonary rehabilitation in the past 12 months prior to study inclusion * unability to attend training sessions on a regular basis for one year * symptomatic coronary heart disease * uncontrolled heart failure * hemodynamically relevant cardiac rhythm disorders * hemodynamically relevant cardiac valvular disorders * uncontrolled arterial hypertension * hypercapnic respiratory failure * severe hypoxemia (i.e. PaO2 \<50 mm Hg resp. SaO2 \<80% at rest) * history of decompensated right heart failure * pulmonary arterial hypertension (PA mean pressure at rest \>20 mm Hg) * severe osteoporosis * severe airway obstruction (FEV1 \<50% predicted, FEV1 \<60% predicted following bronchodilatation) * maximum work rate of less than 50 watt during ergometer testing * uncontrolled asthma * COPD exacerbation * severe adipositas (BMI \>35 kg/m2)

Locations (1)

University Medical Center Hamburg-Eppendorf

Hamburg, Germany

Outcomes

Primary Outcomes

Maximum oxygen uptake

Maximum oxygen uptake measured during unsteady state cycle ergometer test with work increments of 10 watts each minute until exhaustion.

Time frame: One year

Secondary Outcomes

General quality of life

Assessment of general quality of life using the german version of the SF-36 questionaire.

Time frame: One year

Disease-specific quality of life

Assessment of the disease-specific quality of life using the Asthma Quality of Life Questionnaire (AQLQ)

Time frame: One year

Data from ClinicalTrials.gov

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