ALK33-101: A Study of RDC-0313 (ALKS 33) in Adults With Binge Eating Disorder

Inclusion Criteria: * Meet the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, text revised (DSM-IV-TR) criteria for a diagnosis of binge eating disorder (BED) * Display greater than or equal to 3 binge eating days per week * Body mass index (BMI) greater than or equal to 30 kg/m2 * Age of 18 years or older * Women of childbearing potential must agree to use an approved method of birth control for the duration of the study Exclusion Criteria: * Concurrent symptoms of bulimia nervosa or anorexia nervosa * Suicidal ideation * DSM-IV-TR diagnosis of substance abuse or dependence (except nicotine or caffeine) within 6 months prior to randomization * Positive urine toxicological screen for benzodiazepines, opioids, amphetamine/methamphetamine, or cocaine at screening or randomization * Women who are pregnant or breastfeeding * Participation in a psychological or weight loss intervention for BED that was initiated within the 3 months prior to screening * Clinically unstable medical disease * History of hepatitis B, hepatitis C, or human immunodeficiency virus (HIV) * History of seizures, including clinically significant febrile seizures in childhood * Current or anticipated need for prescribed opioid medication during the study period * Use of any psychotropic medications (other than hypnotics) * Participation in a clinical trial of a pharmacological agent within 30 days prior to screening