Temporal Pattern of Circulating DNA for Patients Receiving Irradiation

Inclusion Criteria: * Patient must be scheduled to undergo Total Body Irradiation (TBI) as part of a conditioning regime for a Bone Marrow Transplant. OR, Be scheduled to undergo Radiation Therapy treatment for a malignancy or other disease and have a radiation treatment field that contains at least 2 liters of tissue receiving at least 2 Gy radiation dose over the first 5 days of treatment. * Patient must be willing to have blood draws as defined below. * Patient must provide study-specific informed consent prior to study entry. * Hemoglobin≥8. * Age ≥ 18, but not older than age 60. Exclusion Criteria: * Patients not meeting the above inclusion criteria.