The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing morphine consumption and pain, and at the same time improving mobilisation after total knee arthroplasty.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
70
US-guided Adductor-Canal-Blockade with ropivacaine 7,5 mg/ml
US-guided Adductor-Canal-blockade with saline
Department of Anaesthesia, Privathospitalet Hamlet, Frederiksberg, Denmark
Copenhagen, Frederiksberg, Denmark
Department of Surgery and Anaesthesia, Glostrup Hospital
Glostrup Municipality, Glostrup, Denmark
Total morphine consumption
Total morphine consumption at the interval 0-24 hours postoperative.
Time frame: 0-24 hours postoperative
Total morphine consumption
Total morphine consumption at the intervals 0-2, 0-4, 0-8 and 0-26 hours postoperative.
Time frame: 0-26 hours postoperative
Pain during rest
0-100 mm at a visual analogue scale (VAS), at the intervals 2, 4, 8, 24 and 26 hours postoperative, and the area under the curve for the intervals 2-24 and 24-26 hours postoperative.
Time frame: 0-26 hours postoperative
Pain during 45 degrees active flexion of the knee
0-100 mm at a visual analogue scale (VAS), at the intervals 2, 4, 8, 24 and 26 hours postoperative, and the area under the curve for the intervals 2-24 and 24-26 hours postoperative.
Time frame: 0-26 hours postoperative
A change in pain in the placebo group
0-100 mm at a visual analogue scale (VAS), at the intervals 24 and 26 hours postoperative.
Time frame: 24-26 hours postoperative
Postoperative nausea
Nausea scores(0-3)at 2,4,8,24,26 hours postoperative.
Time frame: 0-26 hours postoperative
Zofran consumption
Total zofran consumption at the intervals 0-24 and 24-26 hours postoperative.
Time frame: 0-26 hours postoperative
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Sedation
Seadtion score (0-3) at 2,4,8,24,26 hours postoperative.
Time frame: 0-26 hours postoperative
Mobilisation
Number of seconds it takes to complete the "Timed Up and Go" test, at 20 and 26 hours postoperative.
Time frame: 20-26 hours postoperative
Postoperative vomiting
Number of vomiting episodes at the intervals 0-2,2-4,4-8,8-24,24-26 hours postoperative.
Time frame: 0-26 hours postoperative