The primary objective of this study is to compare the duration of subject reported comfortable contact lens daily wear time in subjects with a history and current complaint of CLDE during a 29-day treatment period of azithromycin ophthalmic solution, 1%, compared to rewetting drops
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
50
1 drop BID for the first 2 days and then 1 drop QD for the remainder of treatment period (29 ± 1 day)
1-2 drops QID for the treatment period (29 ± 1 day)
The Ohio State University, College of Optometry
Columbus, Ohio, United States
Subject-reported comfortable contact lens daily wear time (hours/day) at Week 4 Endpoint
Time frame: 4 weeks
Subject-reported comfortable contact lens daily wear time, excluding Week 4 Endpoint
Time frame: 2 weeks
Subject-reported duration of total contact lens daily wear
Time frame: 4 weeks
Subject-reported rating of overall eye dryness
Time frame: 4 weeks
Contact Lens-Related Dry Eye Questionnaire
Time frame: 4 weeks
Tear hyperosmolarity (mOsm)
Time frame: 4 weeks
Habitual low-contrast visual acuity (LCVA)
Time frame: 4 weeks
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