Recent studies indicate that remote ischemic conditioning can protect the heart and other organs during cardiac surgery. The investigators aim to investigate whether such a stimulus can reduce the incidence of atrial fibrillation or other complications following coronary artery bypass surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
191
Patients will have a automated inflator cuff placed on the upper arm during surgery. The cuff will be used to induce fore arm ischemia by inflation to 200 mmHg for 3 x 5 minutes, interspersed with 5 minutes of no-inflation and thus reperfusion.
Patients will have a automated inflator cuff placed on the upper arm during surgery which will not be inflated.
Academic Medical Center, University of Amsterdam
Amsterdam, Netherlands
Post-operative atrial fibrillation
Time frame: 72 hours
Major cardiovascular and cerebrovascular events
Major adverse events, i.e. death, acute coronary syndrome, stroke.
Time frame: 3 months, 6 months, 1 year
Length of stay
Duration of hospitalization and stay on the ICU
Time frame: 1 week on avarage
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