The objective of the study is to compare subjective appetite ratings and after-meal and 24 hour blood glucose levels within overweight and obese female subjects consuming either a standardized 3 day low calorie diet supplemented with a viscous fibre known as PGX (treatment) or a rice flour (placebo control). Each treatment phase will be 3 days in length and separated by 3 week washout phase, so subjects will also be acting as their own control. Subjects will be randomized to either start with the low calorie diet with PGX or the low calorie diet supplemented with rice flour. We hypothesize that the 3 day LCD with PGX will elicit an improved appetite score compared to the 3 day LCD supplemented with the rice flour placebo control.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
35
powder, 5 grams, 3 times per day at each main meal (breakfast, lunch and dinner) for a total of 3 days
Canadian Centre for Functional Medicine
Coquitlam, British Columbia, Canada
Canadian Center for Functional Medicine
Coquitlam, British Columbia, Canada
Change in the ratings of the variables in the Appetite Visual Analog Scale and the overall Appetite Score.
Time frame: 3 days
Changes in 2-hour postprandial areas under the curve (AUC) and 24 hour blood glucose (CGMS) profiles.
Time frame: 3 days
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