The purpose of this study is to reduce the HIV/HCV incidence among the clients attending community-based methadone maintenance treatment (MMT) , and to prevent the secondary sexual transmission from HIV+ clients to their spouse and sex partners, through intensified comprehensive intervention.
Even though National sentinel surveillance data show that the increase rate of HIV new infections among IDUs in China has become stabilized and slowed down, the new HIV infection is still on the rise, especially in the Yunnan, Guizhou, Guangxi, Xinjiang and Sichuan. This study attempts to further reduce the new infection among MMT clients, and particularly to prevent the transmission from HIV infected clients to their sexual partners with comprehensive intervention. The purposes of this study are: 1. To evaluate the effectiveness of comprehensive interventions to decrease the HIV/STIs incidence among MMT clients. 2. To prevent the sexual transmission between those HIV+ clients and their spouse/partners with intensified intervention.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
12,000
Intensive HIV psychological counseling ,Increased methadone dosage under individualized treatment principle, enhance randomized urine test, strengthen family and social support , partner notification and routine HIV testing, condom promotion, STD referral services.
Center for Disease Control and Prevention,Guangxi Zhuang Autonomous Region
Nanning, Guangxi, China
RECRUITINGCenter for Disease Control and Prevention, Guizhou Province
Guiyang, Guizhou, China
RECRUITINGCenter for Disease Control and Prevention, Sichuan Province
Chengdu, Sichuan, China
HIV incidence rate
Time frame: August 1,2009 to 31,Mar,2011
HCV, Syphilis, HSV-2 incidence
Time frame: 1,Aug.,2009 to 31,Mar,2011
MMT Retention Rate and Lapse/Relapse Rate
Time frame: 1,Aug.,2009 to 31,Mar,2011
Frequency of condom uses
Time frame: 1,Aug.,2009 to 31, Mar,2011
The awareness of HIV-related Information among the clients [
Time frame: 1,Aug.,2009 to 31,Mar,2011
The proportion of discordant couple/partners receiving HIV testing
Time frame: 1,Aug.,2009 to 31,Dec,2010
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Center for Disease Control and Prevention, Xingjiang Uyghur Autonomous Region
Ürümqi, Xingjiang Uyghur Autonomous Region, China
RECRUITINGCenter for Disease Control and Prevention, Yunnan Province
Kunming, Yunnan, China
RECRUITING