A Protein Supplementation and Exercise Strategy to Promote Muscle Protein Anabolism in Frail Elderly People

Wageningen University62 enrolled

Overview

The present study is designed to investigate whether timed protein supplementation will increase skeletal muscle mass in the frail elderly population.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Sarcopenia

Interventions

Protein drinkDIETARY_SUPPLEMENT

Protein drink twice a day during 6 months.

Resistance exercise trainingOTHER

Resistance exercise training twice per week during 6 months.

Placebo drinkDIETARY_SUPPLEMENT

Placebo drink twice a day during 6 months.

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Frail elderly individuals * Able to understand and perform the study procedures Exclusion Criteria: * Type I or type II diabetes (fasted blood glucose level ≥7,0 mmol) * No recent history (within 2 years) of participating in any regular resistance exercise training program (general questionnaire) * Use of anti-coagulation medication (except of Acetyl Salicyl acid) * Presence of coronary heart disease (ECG) * Renal insufficiency (eGFR \<60 mL/min/1.73 m2) * Allergic or sensitive for milk proteins

Locations (1)

Wageningen University

Wageningen, Gelderland, Netherlands