The current study is aimed at determining the normal response to increasing heart rates. For this purpose, atrial pacing will be used to increase heart rate.
Participants will be patients with pacemakers and normal A-V node conduction with a possibility for right atrial pacing mode. Detailed Echo studies will be performed at baseline. Echo studies will be repeated at each pacing stage, stages defined as 10 bpm increments in paced heart rate. Each stage will last 2-3 min or as long as it takes to record the echo study. Heart rate will be increased to 85% of predicted heart rate for age or at to appearance of signs of ischemia. Hemodynamic parameters will be recorded and segmental longitudinal strain will be calculated (as well as other Echo data), for each stage.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
100
The pacing rate will be increased by 10 bps at every stage
Hille Yaffe Medical Ceter
Hadera, Israel, Israel
RECRUITINGSegmental Strain
Segmental Strain by speckle tracking method will be calculated for every stage of each study.
Time frame: approx. 20 minutes
LV function
Parameters of systolic and diastolic function will be calculated at each stage.
Time frame: Approx. 20 minutes
David S. Blondheim, MD
CONTACT
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