SPECT/CT in the Diagnosis of Dementia

Kuopio University Hospital82 enrolled

Overview

Aim of the study is to evaluate whether Tc-99m-ECD-SPECT/CT enhances early diagnosis of dementia in two specific patient groups: (1) patient with mild cognitive impairment, and (2) patient with possible symptoms and signs of frontotemporal dementia. Evaluation of SPECT/CT data is performed both by visual and quantitative voxel-based analyses (Statistical Parametric Mapping). The final diagnosis is based on up to four years clinical follow-up.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Dementia

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria (one of these): * healthy control * mild cognitive impairment (recruited from a population based data) * clinically suspected frontotemporal dementia (unset diagnosis) Exclusion Criteria: * unable to be scanned with SPECT/CT

Locations (1)

Kuopio University Hospital

Kuopio, Finland

Outcomes

Primary Outcomes

Final diagnosis

(1) controls, (2) stable mild cognitive impairment (MCI), (3)MCI converted to Alzheimers's disease (AD), (4) frontotemporal dementia (FTD), suspected FTD converted to AD, (5) other final diagnoses

Time frame: 4 years

Data from ClinicalTrials.gov

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