The purpose of this research is to determine whether athletes with concussion have changes in cortical excitability. Single and paired transcranial magnetic stimulation (TMS) can be used as reliable neurophysiological marker of motor cortex reorganization in athletes with concussions. This study also aims to determine whether modulation of cortical activity by a powerful technique of noninvasive brain stimulation (tDCS) results in a different cortical response as compared with sham tDCS.
This study is a multicenter study with investigators from other institutions (Dr. Alvaro Pascual-Leone and Dr. Hugo Theoret).
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
1
Each type of stimulation will be administered with a time interval of a week in between to prevent any carryover affects.
Spaulding Rehabilitation Hospital
Boston, Massachusetts, United States
Cortical excitability and cortical plasticity assessment
TMS and tDCS
Time frame: Baseline, 1st, 2nd and 3rd week
Cognitive functioning in athletes with concussion compared to athletes without concussion
Will use the Immediate Postconcussion Assessment and Cognitive Test (IMPACT): a neuropsychological test battery that measures aspects of cognitive functioning including attention, memory, reaction time and information processing speed.
Time frame: Baseline, 1st, 2nd and 3rd week
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