The purpose of this study is to determine whether the novel treatment of transcranial direct current stimulation (tDCS) could decrease the pain perception of those with spinal cord injury. We will also determine whether these changes are correlated with the clinical outcome (pain reduction).
The active tDCS stimulation sessions will be compared to sham stimulation. More study details will be provided by Spaulding Rehabilitation Hospital.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
24
Stimulation will be applied at 2 mA for a total of 20 minutes.
Spaulding Rehabilitation Hospital
Boston, Massachusetts, United States
Neurophysiological activity changes after treatment with tDCS
Magnetic resonance spectroscopy (MRS), electroencephalogram (EEG), transcranial magnetic stimulation (TMS)
Time frame: baseline, 2 weeks treatment and follow up (2 weeks)
Pain changes
(i) Demographic Data; (ii) Visual analog scale (VAS) for pain; (iii) Analgesic use; (iv) Quality of Life Scale (QOLS); (v) Patient Global Assessment (PGA); (vi) Clinical Global Impression (CGI); (vii) Beck Depression Inventory (BDI); (viii) Visual Analog Scale (VAS) for anxiety; (ix) tDCS Side Effects Questionnaire; (x) Mini-mental status exam; and (xi) Validation of Blinding
Time frame: Baseline, 2 weeks treatment and follow up (2 weeks)
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