Impact on the Proteolysis of Obesity in Dialysis

Inclusion Criteria: * Common Criteria for patients and healthy volunteers: * Males and females. * Age between 30 to 70 years. * Body Mass Index: Selection criteria for the obese: BMI\> 30 kg/m2, Selection criteria for non-obese subjects: 18.5 \<BMI \<25 kg/m2. * Biological Review considered satisfactory by the investigator based on the topics covered: chronic renal (obese or not) or healthy volunteers. * Serology HIV and HCV negative. * Subject giving his written informed consent * Affiliated to National Health Insurance Specific criteria for kidney chronic patients in hemodialysis: * Patients on hemodialysis since more than 6 months. * Patients with a clinical stable condition defined by the absence of progressive disease. Specific criteria for healthy volunteers: * Subject considered as healthy after clinical examination and medical questionnaire * Topic willing to be included in the national register of healthy volunteers. Exclusion Criteria: * Common Criteria for patients and healthy volunteers: * Subject under 30 or over 70 years. * Pregnant or lactating. * For women of childbearing age: β-hCG assay positive and not have to contraceptives reliable (oral contraceptive, IUD, implant or hormone patch). * Medical or surgical history (judged by the investigator to be incompatible with the study). * Diabetics (type 1 or 2). * Blood donation in the two months preceding the study. * Special dietary needs (vegetarian, vegan, ...). * Heavy alcohol consumption (\> 2 to 3 glasses per day depending on sex) or presence of an addiction. * Tobacco significant (\> 5 cigarettes / day or equivalent in cigars or pipe tobacco). * Intense sporting activity (\> 5 hours / week). * Being in exclusion on the National Volunteers Data file * Subjects deprived of their liberty by judicial or administrative. Specific criteria for kidney chronic patients in hemodialysis: * Patients treated with peritoneal dialysis. * Patients treated with daily hemodialysis. * Albuminemia \<35 g / l and transthyrétinémie \<300 mg / l Specific criteria for healthy volunteers: * Refusal to be registered on the National Volunteers Data file * Currently participating or who having got 4500€ in this year before to have participed in another clinical trial