Effect of Cannabis on Simulated and Actual Driving in Healthy Subjects

Inclusion Criteria: * Weight +/- 10% of ideal weight * Tobacco smoker moderate * Having already smoked of the cannabis (less 1 time per month) * Not consuming in a way exaggerated by some coffee, tea or cola * Not having acute or chronic pathologies * Normal electrocardiogram * Not taking a drug interfering with the study * Not presenting disorder of sleeping * Having a driving license for at least 3 years and driving more 3000 km per year * Normal acuteness or corrected visual acuteness and normal vision of colors * Reachable and available during the study * No nausea or vomit during using of a driving simulator * Having a national insurance scheme * Volunteer Exclusion Criteria: * Women * Weight deviating of 10% of ideal weight * Consuming moreover 5 cup of caffeine drinks * Drinking alcohol regularly * Acute or chronic pathologies interfering with the study * Abnormal electrocardiogram * Asthmatic * Dependence present or spent in a psychotropic substance * Presenting an anxious or depressive syndrome * Circadian typology (Horne et Ostberg) * Positive control in the cannabis in urines the day of the balance assessment of inclusion * Positive control in alcohol the day of the balance assessment of inclusion * Participating in another clinical study * Having collected an upper total amount of compensations allowances * Deprived of freedom further to a court or administrative order * Risk of not observance * Duration average of sleep of 3 nights previous every session lower than 80 % of the average duration of sleep which the volunteer thinks of needing to be in shape