Study Assessing Safety and Efficacy of DE-101 Ophthalmic Suspension in Dry Eye Patients

Inclusion Criteria: * confirmed diagnosis of dry eye defined by protocol * 18 years or older, and sign written informed consent * negative pregnancy test and utilizing reliable contraceptive throughout study Exclusion Criteria: * use of any topical ocular medications * any ocular surgery within 90 days of study * laser refractive surgery within one year of study * ocular, lid disease/abnormalities that may interfere with the study * corneal transplants * uncontrolled systemic conditions * females who are pregnant or nursing or planning a pregnancy, or females of childbearing potential who are not using a reliable method of contraception * participated in another drug trial within 30 days prior to study