The aim of the study is an intra-individual comparison of skin conditions in addition to a patient based assessment of product appearance in the topical treatment of atopic eczema.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
20
Almirall Investigational Sites#1
Hamburg, Germany
Change in total sum score of Clinical signs
scoring of clinical parameters (erythema, edema, crusting, excoriation, lichenification, dryness, itching) will be performed on a 4 point scale by investigator, comparing data from baseline (day1) vs end of trial (day15)
Time frame: 15 days
change in skin hydration
measurement will be performed by corneometry, comparing data from baseline (day1) vs end of trial (day15)
Time frame: 15 days
Time dependancy of Skin penetration
subject's 5 point assessment of perceived skin penetration will be performed for 2 hours after the first application
Time frame: 2 hours
patient overall assessment
patient's intraindividual 5 point assessment on product on perception will be performed at end of trial (day15)
Time frame: 15 days
Number of skin reactions per patient as a measure of safety and tolerability
scoring will be performed by investigator
Time frame: 15 days
Number of Adverse Events per patients as a measure of safety and tolerability
reporting will be performed by investigator
Time frame: Daily
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