Cardiovascular Safety of Xenon in General Anaesthesia, in Patient With Cardiovascular Risk in Non Cardiac Surgery

Inclusion Criteria: * Age ≥ 18 years * Scheduled for atherosclerotic vascular elective surgery with presumed fast-track, * Cardiac ischaemic risk supported by: * History of myocardial infarction older than 1 month and/or * Documented Stable angina (asymptomatic ± medical treatment) and/or * History of coronary revascularisation, and/or * Surgical Risk Index ("Lee" index) ≥ 3. * Written informed consent Exclusion Criteria: * Unstable angina within the last 30 days, * Non controlled arterial Hypertension . * Severe Cardiac heart Failure (NYHA IV) * Severe Chronic Obstructive Pulmonary Disease * Patient already randomized in another ongoing clinical trial * Patient with recent myocardial infarction (M.I) (less than one month ) * Patient already included in a clinical trial * History of hypersensitivity to study drugs( i.e Xenon, propofol, sevoflurane, desflurane, isoflurane) * Malignant hyperthermia * Documented Elevated intracranial pressure * Preeclampsia or eclampsia * Pregnancy and lactation * Presumed uncooperativeness or legal incapacity