Corneal Endothelial Cell Density Changes In Healthy Subjects, When Administered ISV-403 for 5 Days

Inclusion Criteria: * Must have pin-holed Snellen visual acuity equal to or better than 20/40, in both eyes * Must be in good health (no current or past relevant medical/ocular history) based on the judgment of the Investigator * Must be willing to discontinue contact lens wear for the duration of the study Exclusion Criteria: * Known hypersensitivity to fourth generation fluoroquinolone (SS734) or to any of the ingredients in the study medication Investigator determines could interfere with the study * History of extended or continuous wear contact lens use other than silicone hydrogels * History of intraocular surgery * Any topical ophthalmic medication, including tear substitutes, that cannot be discontinued during the study * Participation in an ophthalmic drug or device research study within the 30 days prior to entry in this study