Prevalence of Malnutrition in Oncologic Patients

N/ACompletedNCT01120483

Charite University, Berlin, Germany400 enrolled

Overview

Malnutrition is a common phenomenon in cancer patients. Deteriorated nutritional status is associated with poor clinical outcome. The purpose of this study is to determine the prevalence of hospital malnutrition and its impact on functionality, quality of life and mortality in cancer patients and to test the reference percentiles of phase angle values (Bosy Westphal et al JPEN 2006) as indicator of cancer cachexia and predictor of mortality. Hypothesis: The fifth reference percentile of the phase angle norm values is a prognostically relevant cut off value indicating cancer cachexia in terms of malnutrition, fatigue and impaired functional status, as well as predictive of 6-month mortality

Study Type

OBSERVATIONAL

Enrollment

400

Conditions

Cancer Malnutrition

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients suffering from cancer. * Patients who have signed a written Informed Consent. Exclusion Criteria: * Patients with implanted pacemaker or defibrillator * Patients with neuromuscular disease or hemiplegia.

Locations (1)

Department of Gastroenterology, Charité Universitätsmedizin Berlin, Campus Mitte

Outcomes

Primary Outcomes

Prevalence of malnutrition

Phase angle (bioelectrical impedance analysis) Nutritional status(SGA), muscle function (grip strength)

Time frame: 1 day

Secondary Outcomes

Quality of life

Quality of life is determined with the questionnaire QLQ C-30 of the European Organisation for Research and Treatment of Cancer (EORTC)

Time frame: 1 day

Mortality

Patients are going to be contacted via telephone six months after the first assessment. Deceased patients will be determined by the local death register

Time frame: 6 months

Depression

Risk for depression is assessed using the Center for Epidemiological Studies Depression Scale (CES-D)

Time frame: 1 day