Crux Biomedical Vena Cava Filter Study - United States

Inclusion Criteria: * Patient has a permanent or temporary risk of Pulmonary Embolism * Patient or legal guardian must provide written informed consent * At least one of the following conditions * Proven PE * Recurrent PE despite adequate anticoagulation * Contraindication to anticoagulation * Inability to achieve/maintain therapeutic anticoagulation * Iliocaval DVT * Large, free-floating proximal DVT * Massive PE treated with thrombolysis/thrombectomy * Chronic PE treated with thrombectomy * Procetion during thrombolysis for iliocaval DVT * PE with limited cardiopulmonary reserve * Poor compliance with anticoagulation medication * High risk of injury worsend by anticoagulation * Multi-trauma patient with high risk of PE * Surgical patients at high risk of PE * Medical condition with high risk of PE * Patient has documented vena cava diameter of 17-28mm * Patient has IVC anatomy suitable for infra-renal placement * Patient willing to be available for the appropriate follow up. Exclusion Criteria: * Age \<18 years old * Patient has any one of the following conditions * Renal vein thrombosis * IVC thrombosis extending to te renal veins * Duplicate IVC * Gonadal vein thrombosis * Requires supra-renal placement * Uncontrolled infectious disease * Risk of aseptic PE * Uncontrolled coagulopathy * Existing inferior vena cava filter implant * Life expectancy less than 6 months * Pregnant or planning a pregnancy in the next 6 months * Condition that inhibits radiographic visualization of the IVC * Known allergy or intolerance to polytetrafluoroethylene (PTFE) or Nitinol * Known hypersensitivity to contract which cannot be pretreated * Access vessels preclude safe insertion of delivery system * Participation in another drug or device trial * Unable or unwilling to cooperate with study procedures or required follow-up visits