Crux Biomedical Evaluation of the Crux Inferior Vena Cava Filter 4

Inclusion Criteria: * Patient has a permanent or temporary risk of Pulmonary Embolism. * Patient must provide informed consent At least one of the following conditions - * Proven PE * Recurrent PE despite adequate * Contraindication to anticoagulation * Inability to achieve/maintain therapeutic anticoagulation * Iliocaval DVT * Large, free-floating proximal DVT * Massive PE treated with thrombolysis/thrombectomy * Chronic PE treated with thrombectomy * Protection during thrombolysis for iliocaval DVT * PE with limited cardiopulmonary reserve * Poor compliance with anticoagulation medication * High risk of injury worsening on anticoagulation * Multi-trauma patient with high risk of PE * Surgical patients at high risk of PE * Medical condition with high risk of PE Patients with a documented vena cava diameter of 17-28mm Patient has IVC anatomy suitable for infra-renal placement Patient is willing to be available for the appropriate follow up Exclusion Criteria: * Age \<18 years old * Patient has any one of the following conditions: * Renal vein thrombosis * IVC thrombosis extending to the renal veins * Duplicate IVC * Gonadal vein thrombosis * Requires supra-renal placement * Vena cava diameter of 17-28mm * Uncontrolled infectious disease * Risk of aseptic PE * Uncontrolled coagulopathy * Existing inferior vena cava filter implant * Life expectancy less than 6 months * Pregnant or planning a pregnancy in the next 6 months * Condition that inhibits radiographic visualization of the IVC * Known allergy or intolerance to polytetrafluoroethylene (PTFE) or Nitinol * Known hypersensitivity to contract which cannot be pretreated * Access vessels preclude same insertion of delivery system * Participation in another drug or device trial * Unable or unwilling to cooperate with study procedures or required follow-up visits