Acetaminophen to Prevent Ischemic Oxidative Reperfusion Injury During Percutaneous Coronary Intervention for Acute Myocardial Infarction

Inclusion Criteria: \- Patients presenting with STEMI Exclusion Criteria: * Duration of symptoms \> 12 hours * Suspected LM or proximal LAD occlusion (based on EKG interpretation) * Hemodynamic instability * Acetaminophen use in prior 24 hours * Use of dipyridamole, or Aggrenox, a formulation of aspirin and extended-release dipyridamole, within 48 hours * Current use of the following medications: phenytoin, valproic acid, phenobarbital, topiramate, rifampin, carbamazepine, cyclophosphamide, ritonavir, efavirenz, St. John's Wort * Chronic heavy alcohol use * Chronic liver disease (other than non-alcoholic fatty liver infiltration) * Severe valvular heart disease * Stroke in the past 60 days * Active major bleeding * Major surgery in the past 30 days * Ongoing treatment for active malignancy * Life expectancy less than 12 months as determined by the patient's attending physician * Pregnancy * asthma or severe COPD * active wheezing on presentation * allergy or prior adverse reaction to adenosine