The Effect of Metamin 3D on the Lipid and Glucose in Subjects With Metabolic Syndrome

Inclusion Criteria: * Age between 30 and 75 years * Fasting plasma glucose \>= 100 mg/dl * Triglyceride \>= 150 mg/dl * one of the criteria following 1. HDL \<40 mg/dl in man or \<50 mg/dl in woman 2. Blood pressure \>= 135/85 mmHg or anti-hypertension drug treatment 3. Waist \>90cm in man or 80cm in woman * Signed the inform consent Exclusion Criteria: * Fasting plasma glucose \> 180mg/dl * Treated by more than two types oral hypoglycemic agents in past 3 months * Treated continuously by anti-lipid agents for 3 months in past 6 months * Treated by thiazolidinedione or digitalis at present * Serum creatine \> 2.5mg/dl * Liver function (GOT or GPT) more than 3-fold upper limit * Severe systemic disease by investigator's judgement * Pregnant or nursing women * Enrolled in other clinical study in recent 1 month