Monthly Follow up of Interferon Gamma Releasing Assay (IGRA) Among Health-care Workers Treating Tuberculosis (TB) Patients

Seoul National University Hospital49 enrolled

Overview

Interferon gamma releasing assay(IGRA) is useful to diagnose latent tuberculosis. However,IGRA responses could show within-subject variability. We wanted to determine long-term IGRA variability in health-care workers who continuously expose to tuberculosis patients.

IGRA will be performed monthly in health-care workers with continuous exposure to tuberculosis patients for 1 year.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Tuberculosis

Interventions

Blood samplingsOTHER

About 3.5ml of blood will be drawn from the participants monthly.

Eligibility

Sex: ALLMin age: 20 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Health care workers who are continuously exposed to TB patients Age \> 20 years Exclusion Criteria: * Pregnant Active TB Use of immunosuppressants

Locations (1)

Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine and Lung Institute of Medical Research Center, Seoul National University College of Medicine

Seoul, South Korea

Outcomes

Primary Outcomes

Results of interferon-gamma releasing assay

Time frame: monthly for 1 year

Data from ClinicalTrials.gov

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