The Effect of Gabapentin (Neurentin) and Pregabalin (Lyrica) in Pain Reduction After Photorefractive Keratectomy

Phase 1UnknownNCT01122004

Shahid Beheshti University of Medical Sciences

Overview

The studied patients will be given randomly one of three following drugs1:Gabapentin2: Pregabalin or placebo for 3 days after Photorefractive keratectomy surgery. The pain will be measured based on visual analog scale(VAS) on the day of operation and on the 3 rd day (morning, evening) and then compared among three groups.

Study Type

INTERVENTIONAL

Purpose

TREATMENT

Conditions

Refractive Errors

Interventions

PregabalinDRUG

Eligibility

Sex: ALLMin age: 17 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients candidate for PRK, 17\<age\<70 Exclusion Criteria: * use of any systemic analgesic drugs, drug intolerance, need of systemic or topical administration of NSAIDs or eye drops for allergy and glaucoma, dry eyes, pregnancy, breast feeding

Locations (1)

Ophthalmic Research Center

Tehran, Tehran Province, Iran

RECRUITING

Outcomes

Primary Outcomes

pain degree based on visual analog scale(VAS)

Central Contacts

Amir faramarzi, MD

CONTACT

+982122585952

Data from ClinicalTrials.gov

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