A Study of the Safety and Pharmacokinetics of MFGR1877S in Patients With Relapsed or Refractory t(4;14)-Positive Multiple Myeloma

Inclusion Criteria: * ECOG performance status of 0, 1, or 2 * Life expectancy of at least 12 weeks * Histologic documentation of previously treated t(4;14)-positive multiple myeloma for which no effective standard therapy exists Exclusion Criteria: * Prior use of any monoclonal antibody before study treatment * Treatment with radiotherapy, thalidomide, lenalidomide, bortezomib, any chemotherapeutic agent, or treatment with any other investigational anti-cancer agent within 4 weeks of study treatment * Completion of autologous stem cell transplant within 6 months prior to study treatment * Prior allogeneic stem cell transplant * History of severe allergic or anaphylactic reactions to monoclonal antibody therapy * Evidence of significant, uncontrolled concomitant diseases, including significant cardiovascular disease or pulmonary disease * Known active bacterial, viral, fungal, mycobacterial, parasitic, or other infection at screening or any recent major episode of infection requiring treatment with IV antibiotics or hospitalization prior to study treatment * Recent major surgery (prior to study treatment), other than for diagnosis * Presence of positive test results for Hepatitis B or Hepatitis C * Known history of HIV seropositive status * Women who are pregnant or lactating * Childbearing potential without agreement to use effective form of contraception for the duration of the study