Neugranin in Breast Cancer Participants Receiving Doxorubicin/Docetaxel

Double-Blind Phase: Duration of Severe Neutropenia in Cycle 1

Severe neutropenia was defined as Grade 4 neutropenia (absolute neutrophil count \[ANC\] \<0.5 x 10\^9/liter \[L\]). The duration of severe neutropenia was calculated by cycle as the number of days from the first day in which the ANC fell below 0.5 x 10\^9/L after beginning a chemotherapy cycle until the participant had an ANC ≥0.5 x 10\^9/L within the cycle.

Time frame: Cycle 1 (cycle length = 21 days)

Open-Label Phase: Duration of Severe Neutropenia in Cycle 1

Severe neutropenia was defined as Grade 4 neutropenia (ANC \<0.5 x 10\^9/L). The duration of severe neutropenia was calculated by cycle as the number of days from the first day in which the ANC fell below 0.5 x 10\^9/L after beginning a chemotherapy cycle until the participant had an ANC ≥0.5 x 10\^9/L within the cycle. There was no planned statistical analysis for the open-label phase arm.

Time frame: Cycle 1 (cycle length = 21 days)