Evaluation of Simplified Antiretroviral Treatment Strategies in HIV Infected Children Treated by Antiretroviral (ARV) Before One Year of Age

Inclusion Criteria for antiretroviral treatment initiation: * infant follow-up in one of the trial site * HIV-1 infection diagnose by RT PCR after 6 weeks of life * age between 3 and 12 month at the antiretroviral treatment initiation * naive of antiretrovirals except if received for the prevention of mother to child HIV transmission * HB\>=7 g/dl, neutrophiles\>750/mm3, creatinin\<3xULN, TGO and TGP\<3xULN * signed informed consent Exclusion Criteria for antiretroviral treatment initiation: * HIV-2 infection or HIV-1/HIV-2 co-infection * Known intolerance to one of the trial treatment * HB\<7 g/dl, neutrophiles\<750/mm3, creatinin\>3xULN, TGO or TGP\>3xULN Inclusion Criteria for randomisation at 12 months in the simplification phase: * age 24 months at most * virological success define as 2 consecutive indetectable HIV RNA measured by RT PCR at least 3 months apart. Exclusion Criteria for randomisation at 12 months in the simplification phase: * virological failure after the first 12 months of antiretroviral treatment