Pilot Study of Remote Ischemic Preconditioning in Heart Failure

University Health Network, Toronto22 enrolled

Overview

The purpose of this study is to determine the effect of remote ischemic preconditioning on exercise capacity in patients with heart failure.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Heart Failure Left Ventricular Dysfunction

Interventions

Remote ischemic preconditioningOTHER

4 cycles x 5 mins upper limb blood pressure cuff inflation 20mmHg above systolic blood pressure

Sham ControlOTHER

4 cycles x 5mins blood pressure cuff inflation to 10mmHg

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * LV ejection fraction \<40% * NYHA functional class II-IV * Non ischemic cardiomyopathy * Stable Exclusion Criteria: * recent cardiovascular hospitalization (within last 4 weeks) * ischemic cardiomyopathy * diabetes mellitus * peripheral neuropathy * ventricular assist device * contraindications to exercise stress testing

Locations (1)

Toronto General Hospital

Toronto, Ontario, Canada

Outcomes

Primary Outcomes

Exercise performance - VO2, exercise time, exercise workload, anaerobic threshold

Time frame: 1 week

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.