The Effect of DHEA on Markers of Ovarian Reserve in Women With Diminished Ovarian Reserve

Early Phase 1TerminatedNCT01129830

Virginia Center for Reproductive Medicine200 enrolled

Overview

This prospective study evaluates the effect of DHEA supplementation on markers of ovarian reserve in women with diminished ovarian reserve.

Ovarian reserve markers, such as FSH, estradiol, AMH, ovarian volume and antral follicle counts will be monitored on DHEA supplementation in a prospective fashion.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

200

Conditions

Infertility

Interventions

dehydroepiandrosteroneDIETARY_SUPPLEMENT

DHEA supplementation 25 mg tid for 3 months

Eligibility

Sex: FEMALEMin age: 21 YearsMax age: 44 Years

Medical Language ↔ Plain English

Inclusion Criteria: * infertile women with diminished ovarian reserve Exclusion Criteria: * women \> 45

Locations (1)

Virginia Center for Reproductive Medicine

Reston, Virginia, United States

Outcomes

Primary Outcomes

live birth rate

Live birth rate will be monitored for women who took DHEA supplementation

Time frame: 3 years

Secondary Outcomes

number of oocytes

Number of retrieved oocytes for patients undergoing IVF will be monitored along with ovarian response

Time frame: 3 years

Data from ClinicalTrials.gov

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