Cytokine Assay for Early Identification of Pediatric Stem Cell Transplant Recipients

Stanford University26 enrolled

Overview

The aim of our study is to determine whether a clinically relevant laboratory measurement (of seven specific immunologic biochemicals in the blood) can identify which bone marrow transplant recipients are likely to progress to respiratory failure. Our ultimate goal is to devise a comprehensive and inclusive laboratory test that is effective at determining who is likely to go on to respiratory failure, in order to facilitate early medical intervention.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Blood Stem Cell Transplant Failure

Eligibility

Sex: ALLMax age: 21 Years

Medical Language ↔ Plain English

Inclusion Criteria:- Hematopoietic stem cell transplantation (HSCT) for any indication. * Patients will range from age 0 to age 21. There is no gender restriction. We expect the male to female ratio to end up being about 50/50 * Ability to understand and the willingness to sign a written informed consent document.

Locations (1)

Stanford University School of Medicine

Stanford, California, United States

Outcomes

Primary Outcomes

Compute median flourescence intensity, standard curves, and estimated pg/mL for each cytokine.

Time frame: weekly during hospitalization for transplant

Data from ClinicalTrials.gov

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