A Multicenter Comparative Study of the ReCell Device and Autologous Split-thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries

Inclusion Criteria: * The subject requires primary skin grafting as a result of an acute thermal burn injury * The area of the burn injury is at least 200cm2 (1% TBSA in adults) if a contiguous wound, or at least 100cm2 for each of 2 noon-contiguous wounds * The area of total burn injury is 1-20% TBSA * The burn injured area can be divided into two treatment areas ( control and treatment) with 100-320cm2 area for each treatment type * The study treatment area is a second degree burn injury * The subject is between 18-65 years of age * The subject is willing to complete all follow-up evaluations required by the study protocol * The subject is to abstain from any other treatment of the wound(s) for the duration of the study unless medically necessary * The subject agrees to abstain from enrollment in any other clinical trial for the duration of the study * The subject and/or guardian are able to read and understand instructions and give informed, voluntary, written consent * The subject is able and willing to follow the protocol requirements Exclusion Criteria: * The subject's burn injuries were caused by chemicals, electricity, and/or radioactive substances * The total subject burn injury is less than 1% or more than 20% TBSA * The subject has a microbiologically proven pre-existing local or systemic bacterial infection * The subject has been receiving a systemic antibiotic for more than 48 hours prior to grafting * The subject is known to have a pre-existing condition that may interfere with wound healing ( e.g. malignancy, diabetes, or autoimmune disease) * The subject is unable to follow the protocol * The subject is taking medication known to have an effect on wound healing or skin pigmentation ( e.g. systemic corticosteroids, retinoids, etc) * The subject has other concurrent conditions that in the opinion of the investigator may compromise patient safety or study objectives * The subject has a known hypersensitivity to Trypsin or Compound sodium Lactate for Irrigation (Hartmann's) solution