Cheese and Human Health

University of Copenhagen60 enrolled

Overview

The aim of this study is to examine if a diet rich in cheese will have a beneficial effect on risk markers of cardiovascular disease compared to a diet rich in butter. The primary parameters are total cholesterol as well as LDL-, HDL cholesterol and triacylglycerol (TAG). The secondary parameters are hsCRP, markers of insulin resistance, fasting insulin and glucose (HOMA). Furthermore bloodpressure is measured.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Cardiovascular Disease

Interventions

cheeseOTHER

the effect of cheese intake versus butter intake on blood lipids (primarily)

Eligibility

Sex: ALLMin age: 20 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Sign written consent * Age: 20-70 * BMI: 20-32 * Refrain from dietary supplements and blood donations prior to, and during the study Exclusion Criteria: * Known or suspected abuse of alcohol, drugs or medication * Poor compliance * Current or previously cardiovascular disease * Diabetes Mellitus or other severe chronic disease, including severe allergies

Locations (1)

Department of Human Nutrition

Frederiksberg, Denmark

Outcomes

Primary Outcomes

Total cholesterol

Time frame: 6 weeks

LDL cholesterol

Time frame: 6 weeks

HDL cholesterol

Time frame: 6 weeks

Triglyceride

Time frame: 6 weeks

Secondary Outcomes

Insulin

Time frame: 6 weeks

Glucose

Time frame: 6 weeks

fasting hsCRP

Time frame: 6 weeks

Blood pressure

Time frame: 6 weeks

Data from ClinicalTrials.gov

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