Stem Cell Therapy for Type 2 Diabetes Mellitus

Inclusion Criteria: 1. Free will taking part in the study and ability to provide written informed consent; 2. Type 2 diabetes mellitus (as guideline WHO, 1999); 3. Age 18-75 years old，Male/Female; 4. 19≤Body mass index (BMI)≤30㎏/㎡; 5. Fast blood glucose (FBG)≥7.0 mmol/L, and HbAc1≥7％; 6. Intravenous insulin tolerance test（ITT）indicate patient being insulin resistance; 7. Not pregnant or nursing; 8. Negative pregnancy test; 9. Fertile patients will use effective contraception. Exclusion Criteria: 1. Severe concurrent medical condition (e.g., serious heart disease, lung disease, or hematopoietic dysfunction, or liver dysfunction, or kidney dysfunction); 2. Active infection requiring treatment; 3. Unexplained febrile illness; 4. Known immunosuppressive disease, e.g. HIV infection, or hepatitis B or C infection.