Stem Cell Therapy for Type 1 Diabetes Mellitus

Inclusion Criteria: 1. Free will taking part in the study and ability to provide written informed consent. 2. Confirmed diagnosis of type I diabetes for at least 2 years 3. Insulin-dependent. 4. Age 18-50 years, Male/Female. 5. FBG≥7.0 mmol/L, and HbAc1≥7％. 6. Not pregnant or nursing. 7. Negative pregnancy test. 8. Fertile patients will use effective contraception. Exclusion Criteria: 1. Presence of acute diabetic complications in the acute stage as recent myocardial infarction, recent cerebral vascular accident (CVA) or acute renal failure. 2. Severe concurrent medical condition (e.g. lung disease, or hematopoietic dysfunction, or liver dysfunction). 3. Active infection requiring treatment. 4. Known immunosuppressive disease, e.g. HIV infection, or hepatitis B or C infection.