The purpose of this study is to examine the the efficacy of adjunctive nicotine replacement therapy when used in combination with the contingency management (CM) + cognitive behavioral therapy intervention. Subjects will be randomly assigned to receive either a nicotine transdermal patch or a placebo patch as well as being randomly assigned to receive either CM or no CM; all subjects will receive cognitive behavioral therapy. We hypothesize that that subjects receiving both active nicotine patch and CM will have higher rates of abstinence from tobacco than subjects in the other groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
154
Weekly CBT for all subjects
incentives given for abstinence based on urine analysis
14mg ir 21mg doses based on weight and #cigs/day
CMHC
New Haven, Connecticut, United States
Abstinence Rates at the End of Treatment
Our primary outcome will be point prevalence abstinence at the end of the treatment period defined as any self-report of cigarette use during the seven days prior to the last appointment confirmed by urine analysis.
Time frame: 6 weeks
Continuous Abstinence During Treatment
We will also examine continuous abstinence during the six week treatment period by urine analysis each week.
Time frame: 6 weeks
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